Professor Saeed Mirsadraee

Professor Mirsadraee received his medical degree from Shiraz University of Medical Sciences, then undertook his research training at the University of Leeds — a Postgraduate Diploma in Health Research followed by a PhD — alongside specialist radiology training at Leeds Teaching Hospitals. He holds Membership of the Royal College of Surgeons, Fellowship of the Royal College of Radiologists, and Fellowship of the Royal College of Physicians of Edinburgh.

He was appointed Senior Clinical Lecturer at the University of Edinburgh in 2010, working within the university's Clinical Research Imaging Centre across advanced CT and MRI, thoracic imaging and medical education. His review of the seventh edition of the lung-cancer TNM staging system became a widely cited contribution to the radiological literature. In Edinburgh he established the Edinburgh Cardiac CT Course — a programme that trains physicians and radiologists in cardiac CT with an international faculty — which he continues to direct alongside Professor Edwin van Beek.

He was appointed consultant cardiothoracic radiologist at Royal Brompton and Harefield Hospitals in 2015, and Professor of Practice in Cardiovascular Imaging at Imperial College London's National Heart and Lung Institute in March 2016. At Imperial, his research concentrates on what CT can reveal about the anatomy and haemodynamics of the aorta and the cardiac valves, in collaboration with clinicians, engineers and computational scientists.

Advanced cardiovascular CT, centred on complex aortic disease — aneurysm and dissection, before and after repair — and on the cardiac valves. He is the radiology lead for aortic and mitral imaging at Royal Brompton and Harefield Hospitals.

His structural-heart work covers CT planning for transcatheter aortic valve implantation (TAVI), minimally invasive valve surgery and transcatheter mitral interventions — including valve-in-valve and valve-in-ring procedures and the assessment of valvular calcification — where treatment depends on precise three-dimensional assessment of the anatomy, the access route and the fit of the device. He also reports coronary CT angiography, and brings a thoracic-imaging background spanning lung-cancer staging and pulmonary fibrosis.

With biofluid-engineering colleagues at Imperial College London, Professor Mirsadraee's group has developed patient-specific computational models of blood flow in the dissected aorta — the pressure differences between true and false lumen, wall shear stress, and the effect of residual tears after type-A dissection repair — and shown an association between these haemodynamic factors and progressive aortic dilatation after surgery. The aim is personalised risk prediction: identifying the aorta likely to enlarge before the change is visible on diameter measurement alone.

His wider research spans dynamic four-dimensional CT perfusion, the relationship between aortic-leaflet calcification and complications after transcatheter valve implantation, prosthetic-valve leaflet thrombosis after valve-in-valve procedures, and the thrombotic complications of severe COVID-19 in intensive care. He has published over 100 peer-reviewed papers and book chapters, is an advisory editor of Clinical Radiology, and received the Royal College of Radiologists' 2012 award for the best scientific publication in Clinical Radiology.

Professor Mirsadraee established and directs the Edinburgh Cardiac CT Course and the London TAVI CT Course, has led British Society of Cardiovascular Imaging teaching on CT planning of transcatheter mitral procedures, teaches undergraduate radiology at Imperial College London, and contributed to the development of a radiology curriculum for undergraduate medical education.

Professor Mirsadraee reports advanced cardiac CT: coronary CT angiography with calcium scoring, aortic and structural assessment, and CT planning for TAVI and minimal-access surgery. CT and MRI are acquired at partner hospitals and reported at the clinic. Reports are returned to the referring clinician.

To discuss a referral, please contact the clinic.

Nobody chooses a radiologist — but the cardiologist and surgeon who decide a case do. Professor Mirsadraee reads the imaging that the three consultants build their decision on.